High-risk medication in community care: a scoping review.
Dumitrescu I, Casteels M, De Vliegher K, Dilles T.
Eur J Clin Pharmacol. 2020 Feb 5. doi: 10.1007/s00228-020-02838-8. [Epub ahead of print] Review.
Definitions for HRM in community care were used inconsistently among the papers, and various recurrent attributes of the concept HRM were used. Taking the recurrent attributes and the quality score of the definitions into account, the following definition could be derived: "High-risk medication are medications with an increased risk of significant harm to the patient. The consequences of this harm can be more serious than those with other medications". A total of 66 specific medications or categories were extracted from the papers. Opioids, insulin, warfarin, heparin, hypnotics and sedatives, chemotherapeutic agents (excluding hormonal agents), methotrexate and hypoglycaemic agents were the most common reported HRM in community care.